I shared my experience with Exchange 2016 on Windows Server 2016 in the last few weeks.
The most annoying problem, in my opinion, is the Get-Help Issue! I must admit, that I use Get-Help a lot, mostly because the Help is great and why remember every option if you can use Get-Help?
Nevertheless, there is a workaround!
Open a PowerShell Session (On the Exchange Server, or remote) and then type this:
1 | add-pssnapin -name Microsoft.Exchange.Management.PowerShell.SnapIn
|